Predictors of poor retention on antiretroviral therapy as a major HIV drug resistance early warning indicator in Cameroon: results from a nationwide systematic random sampling

Autor: Serge Clotaire Billong, Joseph Fokam, Calixte Ida Penda, Salmon Amadou, David Same Kob, Edson-Joan Billong, Vittorio Colizzi, Alexis Ndjolo, Anne-Cecile Zoung-Kani Bisseck, Jean-Bosco Nfetam Elat
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: BMC Infectious Diseases, Vol 16, Iss 1, Pp 1-9 (2016)
Druh dokumentu: article
ISSN: 1471-2334
DOI: 10.1186/s12879-016-1991-3
Popis: Abstract Background Retention on lifelong antiretroviral therapy (ART) is essential in sustaining treatment success while preventing HIV drug resistance (HIVDR), especially in resource-limited settings (RLS). In an era of rising numbers of patients on ART, mastering patients in care is becoming more strategic for programmatic interventions. Due to lapses and uncertainty with the current WHO sampling approach in Cameroon, we thus aimed to ascertain the national performance of, and determinants in, retention on ART at 12 months. Methods Using a systematic random sampling, a survey was conducted in the ten regions (56 sites) of Cameroon, within the “reporting period” of October 2013–November 2014, enrolling 5005 eligible adults and children. Performance in retention on ART at 12 months was interpreted following the definition of HIVDR early warning indicator: excellent (>85%), fair (85–75%), poor (
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