Prevalence of inappropriate sinus tachycardia and the comparison of the heart rate variability characteristics with propensity score-matched controls

Autor: Evrim Şimşek, Benay Ozbay, Inan Mutlu, Ecem Gurses, Hatice S Kemal, Burcu Yagmur, Levent Hürkan Can
Jazyk: English<br />Turkish
Rok vydání: 2020
Předmět:
Zdroj: Türk Kardiyoloji Derneği Arşivi, Vol 48, Iss 2, Pp 96-102 (2020)
Druh dokumentu: article
ISSN: 1016-5169
DOI: 10.5543/tkda.2019.92735
Popis: Objective: Inappropriate sinus tachycardia (IST) is a syndrome characterized by an elevated resting heart rate with distressing symptoms and no secondary cause of sinus tachycardia. This study was conducted to evaluate both the prevalence of IST among symptomatic patients and heart rate variability (HRV) characteristics. Methods: The records of all consecutive symptomatic patients who had undergone 24-hour Holter monitoring between September 2015 and November 2016 at a single center were retrospectively evaluated. IST was defined as a 24-hour mean heart rate (HR) of ≥90 beats/minute and a resting HR of ≥100 beats/minute in the absence of any secondary cause of sinus tachycardia. All of the study data related to clinical characteristics, symptoms, concomitant diseases, and Holter electrocardiogram parameters were obtained from the electronic hospital records. A propensity age- and sex-matched control group was selected from a non-IST patient cohort. Results: A total of 1865 consecutive patients were evaluated and 32% were excluded due to an inadequate Holter recording period or insufficient quality, atrial fibrillation episodes, atrioventricular block, or >1% atrial or ventricular extrasystoles. Among 1265 patients with sinus rhythm, 4.98% (n=63) had IST. The IST patients were younger (39.6+-17.4 vs. 50.2+-17.2 years; p
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