The Effect of Milk Thistle Extract in the Treatment of Diabetic Nephropathy
| Autor: | Hassan Rezvanian, Ali Kachuei, Ali Mirzapour |
|---|---|
| Jazyk: | perština |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | مجله دانشکده پزشکی اصفهان, Vol 28, Iss 124, Pp 1997-2010 (2011) |
| Druh dokumentu: | article |
| ISSN: | 1027-7595 1735-854X |
| Popis: | Background: Milk thistle has antioxidative effects and may improve renal performance. Our study investigated whether Milk thistle improve renal performance in patients with type II diabetes mellitus nephropathy. Methods: In this clinical trial study, after ethics committee approval, 65 Patients with type II diabetes mellitus were enrolled into a randomized simple sampling, prospective, double-blinded study. In the case group, was gave Milk thistle and control group was given placebo. We measured urine albumin/cratinine (A/C) ratio and eGFR before and after intervention. The gathered data were analyzed by t and paired-t tests. P < 0.05 was regarded as significant level. Finding: The groups were well matched for age, sex, and duration of diabetes. The mean age was 55.9 ± 6.5 and 57.7 ± 7.7 years in case and control groups, respectively. There was not any significant difference between A/C ratio in case and control groups after intervention (P > 0.05); but in case group, after intervention A/C ratio was worse than before it (P < 0.05). Conclusion: The results suggest that Milk thistle did not improve the renal performance in patients with type II diabetes mellitus. |
| Databáze: | Directory of Open Access Journals |
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