Prevalence of multidrug-resistant tuberculosis in suspected childhood tuberculosis in Shandong, China: a laboratory-based study
| Autor: | Xiao-Lin Zhou, Qiao-Pei Chen, Mao-Shui Wang |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Journal of International Medical Research, Vol 48 (2020) |
| Druh dokumentu: | article |
| ISSN: | 1473-2300 03000605 |
| DOI: | 10.1177/0300060519869715 |
| Popis: | Objective Currently, the prevalence of multidrug-resistant tuberculosis (MDR-TB) in childhood tuberculosis (TB) in Shandong, China remains unclear. We retrospectively conducted laboratory-based surveillance in a high TB burden district, to analyze the local prevalence of MDR-TB in childhood TB. Methods We collected data, including microbiological results and demographic and disease information, using a questionnaire and medical records. We used the chi-squared test to compare the prevalence of MDR-TB in childhood TB between two periods: 2008 to 2013 and 2014 to 2018. Results In Shandong, the prevalence of MDR-TB in childhood TB was low, at 5.6%. Between 2008-2013 and 2014-2018 among children with TB, the prevalence of MDR-TB remained unchanged, the proportion with pulmonary TB decreased from 78.3% to 64.9%, and the proportion with a TB contact history decreased from 20.5% to 9.9%. Conclusions The prevalence of MDR-TB among childhood TB in Shandong, China was low and has remained stable over the past years. However, non-tuberculous mycobacterial diseases may be a new challenge in the management of suspected childhood TB. |
| Databáze: | Directory of Open Access Journals |
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