Systematic Review and Meta-Analysis on the Effect of Transdermal Preparations of Sinomenium Acutum on Rheumatoid Arthritis

Autor: Si-Si Du, Qin-Hui Fu, Jian Pei, Hua Zhou, Er-Liang Wang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Chinese Medicine and Culture, Vol 5, Iss 2, Pp 110-118 (2022)
Druh dokumentu: article
ISSN: 2589-9627
2589-9473
00000000
DOI: 10.1097/MC9.0000000000000016
Popis: Abstract. Objective:. We evaluated the efficacy and safety of transdermal preparations of Sinomenium acutum (SA) for rheumatoid arthritis (RA). Methods:. Randomized controlled trials (RCTs) of SA transdermal preparations for RA were extracted from relevant databases and screened in accordance with the inclusion criteria. The Cochrane System Evaluation Manual (version 5.1.0) was used to assess the quality of the included trials. We used the Cochrane Review Manager (version 5.4) to conduct the meta-analysis. Results:. Six trials comprising 436 patients (220 patients in the treatment group and 216 patients in the control group) were analyzed. The meta-analysis indicated that SA transdermal preparations in combination with disease-modifying antirheumatic drugs (DMARDs) enhanced the overall effect (odds ratio [OR] 3.97, 95% confidence interval [CI] [2.25, 7.00], P
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