| Autor: |
Maria Jesús García-Murria, Gerard Duart, Brayan Grau, Elisabet Diaz-Beneitez, Dolores Rodríguez, Ismael Mingarro, Luis Martínez-Gil |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-020-19881-9 |
| Popis: |
Viral analogs of B-cell lymphoma 2 (Bcl2), known as vBcl2s, control apoptosis by interacting with host pro- and anti-apoptotic members of the Bcl2 family. Here, García-Murria et al. report on transmembrane domains (TMDs) in the C-terminal hydrophobic region of herpes- and poxviral vBcl2s, which mediate homo-oligomerization and interactions with cellular Bcl2 TMDs to control apoptosis. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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