Autor: |
Amina Nawal Bahoussi, Pei-Hua Wang, Zi-Hui Ma, Nikita Rani, Changxin Wu, Li Xing |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
Frontiers in Veterinary Science, Vol 9 (2022) |
Druh dokumentu: |
article |
ISSN: |
2297-1769 |
DOI: |
10.3389/fvets.2022.1030522 |
Popis: |
Sustained spread and continuous evolution of CPV-2 generate new genetic information; nevertheless, there is no adopted phylogenetic tool, and parvo virologists still refer to the three antigenic variants. Herein, this report attempted to review the evolutionary trait of CPV-2 and proposed standard reference genomes using the Maximum Likelihood-based phylogenetic analysis and Parsimony-Informative Sites. The analysis revealed three main evolutionary pathways where CPV-2 strains cluster into distinct clades depicted as GI, GII, or GIII, respectively. Furthermore, novel CPV-2 natural recombinants were detected, occurring only between the newly identified strains (2017–2020). Those findings provide unique insights into the evolutionary relatedness of CPV-2, clarify discrepancies between different geographic areas and will contribute to achieving a more reliable CPV-2 genetic and evolutionary genotyping classification. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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