Drug-seeking motivation level in male rats determines offspring susceptibility or resistance to cocaine-seeking behaviour

Autor: Qiumin Le, Biao Yan, Xiangchen Yu, Yanqing Li, Haikun Song, Huiwen Zhu, Weiqing Hou, Dingailu Ma, Feizhen Wu, Yuqing Zhou, Lan Ma
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms15527
Popis: Drug addiction is partially heritable but the non-genetic inheritance mechanisms are not well understood. The authors show that motivation of male rats in response to cocaine self-administration elicit susceptibility and/or decreased resistance to developing addiction like behaviour in offspring.
Databáze: Directory of Open Access Journals