Effectiveness of ultrasonography and shear wave sonoelastography in Sjögren syndrome with salivary gland involvement
| Autor: | Yunus Emre Oruk, Mehmet Burak Çildağ, Can Zafer Karaman, Songül Çildağ |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Ultrasonography, Vol 40, Iss 4, Pp 584-593 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2288-5919 2288-5943 |
| DOI: | 10.14366/usg.21014 |
| Popis: | Purpose This study investigated the effectiveness of major salivary gland ultrasonography (MSGUS) using a new grading system and shear wave elastography (SWE) in evaluating the major salivary glands of patients with Sjögren syndrome (SjS). Methods This prospectively-designed cross-sectional study included 49 SjS patients and 49 healthy controls. Major salivary glands were examined with gray-scale ultrasonography and SWE. A new grading system for salivary glands was developed using MSGUS findings. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of MSGUS and shear wave velocity (SWV) values were investigated. The MSGUS grading system and SWV values were evaluated together by logistic regression analysis. A cutoff value of SWE for salivary glands was determined. Results The sensitivity, specificity, PPV, and NPV of MSGUS were 69.4%, 73.5%, 72.3%, and 70.6% for the submandibular gland and 69.4%, 65.3%, 66.7%, and 68.1% for the parotid gland, respectively. The mean SWV values of the parotid and submandibular glands were significantly higher in SjS patients than in controls (P |
| Databáze: | Directory of Open Access Journals |
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