MRI of lobar holoprosencephaly in a cat with hypodipsic hypernatraemia

Autor: Genya Shimbo, Michihito Tagawa, Masashi Yanagawa, Kazuro Miyahara
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of Feline Medicine and Surgery Open Reports, Vol 4 (2018)
Druh dokumentu: article
ISSN: 2055-1169
20551169
DOI: 10.1177/2055116918801602
Popis: Case summary A 2-year-old neutered female domestic shorthair cat presented with a history of hypodipsia, recurrent hypernatraemia, pelvic limb ataxia and tremor. The serum arginine vasopressin level was low for the serum osmolality. MRI of the brain revealed a failure of separation of the cerebrum, which manifested as absence of the rostral part of the corpus callosum, fornix and septum pellucidum, thus resulting in a single fused ventricle. The diagnosis was lobar holoprosencephaly with hypodipsic hypernatraemia. Relevance and novel information To our knowledge, this is the first description of the MRI characteristics of lobar holoprosencephaly in a cat. This report suggests that MRI examination should be considered for precise diagnosis of hypodipsic hypernatraemia in young cats.
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