Discrepancies and consequences of indirect hemagglutination, indirect immunofluorescence and Elisa tests for the diagnosis of Chagas disease

Autor: Regina Maia de Souza, Vicente Amato Neto
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Revista do Instituto de Medicina Tropical de São Paulo, Vol 54, Iss 3, Pp 141-144 (2012)
Druh dokumentu: article
ISSN: 1678-9946
0036-4665
DOI: 10.1590/S0036-46652012000300005
Popis: Using the indirect hemagglutination (IH), indirect immunofluorescence (IIF) and enzyme linked immunosorbent assay (ELISA) tests for the diagnosis of Chagas disease, 4000 serum samples were examined. This study was conducted with different purposes: clinical interest, research support and parasitological monitoring of those patients with Chagas disease who were treated with heart transplantations. The tests occurred without patient selection and in accordance with the medical requests. The results showed discrepancies and brought about several questions, considering the different results that all three methods showed when considered together. What was found brought about concerns and we suggest the adoption of different measures, aiming to avoid these mismatches in the context of this disease.
Databáze: Directory of Open Access Journals