Population-based study of a free rubella-specific antibody testing and immunization campaign in Chiba city in response to the 2018–2019 nationwide rubella outbreak in Japan

Autor: Kenichi Takeshita, Noriko Takeuchi, Misako Ohkusu, Mihoko Ohata, Mamiko Suehiro, Hisashi Maejima, Hiroki Abe, Fumio Ohta, Yoichi Ohama, Kazuto Tamai, Mana Haraki, Naruhiko Ishiwada
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Human Vaccines & Immunotherapeutics, Vol 17, Iss 6, Pp 1779-1784 (2021)
Druh dokumentu: article
ISSN: 2164-5515
2164-554X
21645515
DOI: 10.1080/21645515.2020.1847584
Popis: Japan has not been able to eliminate rubella; as a result, the large rubella epidemic has occurred. Considering the complicated history of the vaccine policy in Japan, some susceptible populations became infected with rubella, resulting in an outbreak. We conducted a large serosurveillance against rubella in Chiba city after initiating free rubella-specific antibody testing and an immunization campaign during 2018–2019. The total number of rubella specific antibody tests that was conducted in the nationwide campaign and Chiba city original campaign was 8277 and 6104, respectively. The proportion of participants with an antibody titer of ≤1:16 using the hemagglutination inhibition (HI) test was higher in those in their 20–30s. On the contrary, the proportion of participants with an antibody titer of
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