Autor: |
Yuri Kim, Ji Yong Ahn, Hwoon-Yong Jung, Jin Hee Noh, Hee Kyong Na, Kee Wook Jung, Jeong Hoon Lee, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee |
Jazyk: |
English<br />Korean |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
The Korean Journal of Helicobacter and Upper Gastrointestinal Research, Vol 23, Iss 4, Pp 277-282 (2023) |
Druh dokumentu: |
article |
ISSN: |
1738-3331 |
DOI: |
10.7704/kjhugr.2023.0042 |
Popis: |
Objectives The incidence of treatment failures following standard triple therapy (STT) for Helicobacter pylori eradication (HPE) has reached an unacceptable level. Sequential therapy (SQ) has emerged as a promising approach to counteract the escalation of antibiotic resistance. In this study, we used a chronological cohort dataset to conduct a comparative analysis of the eradication rates, compliance, and adverse events associated with the 7-day STT and SQ. Methods A total of 789 patients underwent HPE treatment at Asan Medical Center between July 2013 and August 2017. Among them, 378 received a 7-day STT and 411 received a 10-day SQ. Baseline clinical data and treatment parameters were compared between the two treatment groups. Results SQ demonstrated an eradication rate of 84.7% (348/411), which was superior to that of the 7-day STT (74.1%; p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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