The items in the Chinese version of the Montreal cognitive assessment basic discriminate among different severities of Alzheimer’s disease

Autor: Yan-Rong Zhang, Yun-Long Ding, Ke-liang Chen, Yan Liu, Can Wei, Ting-ting Zhai, Wen-Juan Wang, Wan-Li Dong
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Neurology, Vol 19, Iss 1, Pp 1-7 (2019)
Druh dokumentu: article
ISSN: 1471-2377
DOI: 10.1186/s12883-019-1513-1
Popis: Abstract Background To determine whether items of the Chinese version of the Montreal Cognitive Assessment Basic (MoCA-BC) could discriminate among cognitively normal controls (NC), and those with mild cognitive impairment (MCI), mild Alzheimer’s disease (AD), and moderate-severe (AD), as well as their sensitivity and specificity. Methods MCI (n = 456), mild AD (n = 502) and moderate-severe AD (n = 102) patients were recruited from the memory clinic, Huashan Hospital, Shanghai, China. NC (n = 329) were recruited from health checkup outpatients. Five MoCA-BC item scores were collected in interviews. Results The MoCA-BC orientation test had high sensitivity and specificity for discrimination among MCI, mild AD and moderate-severe AD. The delayed recall memory test had high sensitivity and specificity for MCI screening. The verbal fluency test was efficient for detecting MCI and differentiating AD severity. Conclusions Various items of the MoCA-BC can identify MCI patients early and identify the severity of dementia.
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje