A case of hand urticaria, lip angioedema, and oropharyngeal pruritus induced by Japanese radish through IgE-mediated immediate allergic reaction

Autor: Sumiko Abe, Jun Ito, Sonoko Harada, Hitoshi Sasano, Shoko Ueda, Yuuki Sandhu, Tomohito Takeshige, Yoko Katsura, Norihiro Harada, Kazuhisa Takahashi
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Allergy, Asthma & Clinical Immunology, Vol 17, Iss 1, Pp 1-5 (2021)
Druh dokumentu: article
ISSN: 1710-1492
DOI: 10.1186/s13223-021-00538-1
Popis: Abstract Background Although Japanese radish (Raphanus sativus L.) is a common Japanese ingredient, there are few reports of IgE-mediated immediate food allergy caused by Japanese radish. Case presentation A 48-year-old woman developed urticarial lesions on her hands after grating Japanese radish and also developed lip edema and oral itching when she ate a salad composed of raw Japanese radishes. Skin prick testing was positive to extract of grated Japanese radish. Moreover, immunoblotting analysis showed IgE reactivity in the patient’s serum to a single band at the 18 kDa in grated Japanese radish, suggesting that the heat-labile 18 kDa protein of raw Japanese radish may be a radish-specific antigen. Conclusions To the best of our knowledge, this is the first case report of a patient with hand urticaria, lip angioedema, and oropharyngeal pruritus to raw Japanese radish through IgE-mediated immediate allergic reaction.
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