Neurodevelopmental delay in children exposed to maternal SARS-CoV-2 in-utero

Autor: Viviana Fajardo-Martinez, Fatima Ferreira, Trevon Fuller, Mary Catherine Cambou, Tara Kerin, Sophia Paiola, Thalia Mok, Rashmi Rao, Jyodi Mohole, Ramya Paravastu, Dajie Zhang, Peter Marschik, Sai Iyer, Kalpashri Kesavan, Maria da Conceição Borges Lopes, José Augusto A. Britto, Maria Elisabeth Moreira, Patricia Brasil, Karin Nielsen-Saines
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-024-61918-2
Popis: Abstract It is unclear if SARS CoV-2 infection during pregnancy is associated with adverse neurodevelopmental repercussions to infants. We assessed pediatric neurodevelopmental outcomes in children born to mothers with laboratory-confirmed SARS CoV-2 infection during pregnancy. Neurodevelopmental outcomes of in-utero exposed children were compared to that of pre-pandemic control children in Los Angeles (LA), CA, USA and Rio de Janeiro, Brazil. Bayley Scales of Infant and Toddler Development, 3rd edition (Bayley-III), the gold standard tool for evaluating neurodevelopment until 36 months of age and Ages and Stages Questionnaires (ASQ-3), a frequently used screening instrument for evaluating neurodevelopment in this same age group were the assessment tools used. Developmental delay (DD) was defined as having a score
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