Neurointerface with oscillator motifs for inhibitory effect over antagonist muscles

Autor: Yulia Mikhailova, Anna Pozdeeva, Alina Suleimanova, Alexey Leukhin, Alexander Toschev, Timur Lukmanov, Elsa Fatyhova, Evgeni Magid, Igor Lavrov, Max Talanov
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Neuroscience, Vol 17 (2023)
Druh dokumentu: article
ISSN: 1662-453X
DOI: 10.3389/fnins.2023.1113867
Popis: The effect of inhibitory management is usually underestimated in artificial control systems, using biological analogy. According to our hypothesis, the muscle hypertonus could be effectively compensated via stimulation by bio-plausible patterns. We proposed an approach for the compensatory stimulation device as implementation of previously presented architecture of the neurointerface, where (1) the neuroport is implemented as a DAC and stimulator, (2) neuroterminal is used for neurosimulation of a set of oscillator motifs on one-board computer. In the set of experiments with five volunteers, we measured the efficacy of motor neuron inhibition via the antagonist muscle or nerve stimulation registering muscle force with and without antagonist stimulation. For the agonist activation, we used both voluntary activity and electrical stimulation. In the case of stimulation of both the agonist and the antagonist muscles and nerves, we experimented with delays between muscle stimulation in the range of 0–20 ms. We registered the subjective discomfort rate. We did not identify any significant difference between the antagonist muscle and nerve stimulation in both voluntary activity and electrical stimulation of cases showing agonist activity. We determined the most effective delay between the stimulation of the agonist and the antagonist muscles and nerves as 10–20 ms.
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