Characteristics of Transgender Women Referred to Women's Heart Clinic

Autor: Madeline K Mahowald, Arvind K Maheshwari, Kyla M Lara-Breitinger, Fadi W Adel, Patricia A Pellikka, Caroline J Davidge-Pitts, Todd B Nippoldt, Birgit Kantor, Rekha Mankad
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: American Journal of Preventive Cardiology, Vol 7, Iss , Pp 100223- (2021)
Druh dokumentu: article
ISSN: 2666-6677
DOI: 10.1016/j.ajpc.2021.100223
Popis: Introduction: Transgender women have been reported to have a high burden of cardiovascular disease (CVD) and risk factors based largely on surveys. Our aim was to describe the prevalence of CVD and associated comorbidities among a cohort of older transgender women referred to cardiology as part of their gender-affirming care. Methods: This was a retrospective, cross-sectional study of transgender women at a single institution from 2017 to 2019. Results: Fifty-two consecutive patients were included. The most common reasons for referral were cardiac risk factor management (45%) and pre-operative cardiac risk stratification prior to gender-affirming surgery (35%). The mean age was 57 ± 10 years, 87% were white, and 92% had insurance coverage. Forty-eight patients (92%) were taking gender-affirming hormone therapy; 5 had undergone breast augmentation, 4 had undergone orchiectomy, and 2 had undergone vaginoplasty. The most common comorbidities were depression and/or anxiety (63%), obesity (58%), and hyperlipidemia (54%). Excluding aldosterone antagonists, 46% were on cardiac medications; changes were recommended for 25% of patients: new prescriptions in 9, dose adjustments in 5, and discontinuations in 4. According to the pooled cohort equation, the 10-year risk of atherosclerotic CVD was 9.4 ± 7.7% when the study population was calculated as male and 5.2 ± 5.1% when calculated as female (p
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