Case Report: Refractory Hypotension of GABA B Receptor Autoimmune Encephalitis

Autor: Kong Hanxin, Wang Xiaomin, Ying Hao, Zheng Shuihong
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Frontiers in Neurology, Vol 11 (2020)
Druh dokumentu: article
ISSN: 1664-2295
DOI: 10.3389/fneur.2020.571382
Popis: Introduction: With the development of antibody detection technology, Gamma-Aminobutyric Acid (GABA) B receptor encephalitis is a known autoimmune disease. This paper describes a patient with refractory hypotension who suffered GABA B receptor autoimmune encephalitis.Case Report: We describe a 63-year-old man with GABA B receptor autoimmune encephalitis who had hypotension on day 17 of the disease onset. Despite two rounds of immunoglobulin administration, high-dose intravenous steroid injections and immunosuppressive therapy on day 35 of hospitalization, psychiatric symptoms and seizures were significantly improved; however, the patient's blood pressure remained low.Conclusion: This case study and literature review investigated the impairment of autonomic nerve function and its subsequent management in patients with GABA B receptor autoimmune encephalitis.
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