Association Between Serum Afamin Levels with Nonalcoholic Associated Fatty Liver Disease

Autor: Shenghui Chen, Zhening Liu, Li Cen, Jinghua Wang, Juanwen Zhang, Xiaofeng Zhang, Chengfu Xu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Canadian Journal of Gastroenterology and Hepatology, Vol 2022 (2022)
Druh dokumentu: article
ISSN: 2291-2797
DOI: 10.1155/2022/7175108
Popis: Afamin is a member of the hepatokine that are strongly associated with various metabolic diseases. The relationship between afamin and nonalcoholic fatty liver disease (NAFLD) remains unclear. This study aimed to explore the correlation between serum afamin levels and NAFLD. We analyzed 88 NAFLD patients and 88 age- and sex-matched healthy controls who took their health examinations at the First Affiliated Hospital, Zhejiang University School of Medicine. The association was further confirmed in 22 biopsy-confirmed NAFLD patients and 36 healthy controls. Serum afamin levels were evaluated using an enzyme-linked immunosorbent assay (ELISA). NAFLD patients had significantly higher serum afamin levels than the healthy controls (14.79 ± 5.04 mg/L versus 10.83 ± 3.24 mg/L; P
Databáze: Directory of Open Access Journals