Effects of Reproductive Factors on Lauren Intestinal-Type Gastric Cancers in Females: A Multicenter Retrospective Study in South Korea

Autor: Yoon Ju Jung, Hee Jin Kim, Cho Hyun Park, Seun Ja Park, Nayoung Kim
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Gut and Liver, Vol 16, Iss 5, Pp 706-715 (2022)
Druh dokumentu: article
ISSN: 1976-2283
DOI: 10.5009/gnl210293
Popis: Background/Aims: Gastric cancers (GCs), particularly the Lauren intestinal type, show a male predominance. The aim of this study was to investigate the effects of reproductive factors on GCs in females, according to Lauren classification. Methods: Medical records of 1,849 males and 424 females who underwent radical gastrectomy or endoscopic resection for GCs between 2010 and 2018 were reviewed. The incidences of intestinal-type GCs were compared between males and groups of females stratified according to postmenopausal period. Associations between reproductive factors in females and intestinaltype GCs were analyzed using multivariate models. Results: The proportions of intestinal-type GCs were significantly lower in premenopausal (19%), less than 10 years postmenopausal (30.4%), and 10 to 19 years postmenopausal females (44.1%) than in males (61.0%) (p
Databáze: Directory of Open Access Journals