Multifocal electroretinogram in normal emmetropic subjects: Correlation with optical coherence tomography

Autor: Rajvardhan Azad, Urmimala Ghatak, Yog Raj Sharma, Parijat Chandra
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Band-shaped keratopathy
corneal dystrophy
phototherapeutic keratectomy
phototherapeutic keratectomy with amniotic membrane grafts
scar
and Salzmann nodular degeneration
Kaplan Meier survival analysis
multivariate Cox Proportional Hazard Regression analysis
optical penetrating keratoplasties
Myopia
phakic refractive intraocular lens
refractive surgery
23-Gauge vitrectomy
rhegmatogenous retinal detachment
sutureless vitrectomy
Deep anterior lamellar keratoplasty
endothelial cell density
keratoconus
penetrating keratoplasty
Anterior chamber contamination
cataract surgery
conjunctival flora
diabetics
Cardiovascular disease
diabetes
diabetic retinopathy
framingham risk score
Central macular thickness
multifocal electroretinogram
normative database
optical coherence tomography
Ophthalmology
RE1-994
Zdroj: Indian Journal of Ophthalmology, Vol 60, Iss 1, Pp 49-52 (2012)
Druh dokumentu: article
ISSN: 0301-4738
1998-3689
DOI: 10.4103/0301-4738.91345
Popis: Aim of the Study: To establish the normative database for multifocal electroretinogram (mfERG) parameters in a normal emmetropic population. To correlate the data so obtained with the central macular thickness obtained using the optical coherence tomography (OCT) scan. Materials and Methods: mfERG data were obtained from 222 eyes of 111 emmetropic subjects. The amplitude (nv/deg 2 ) and implicit times (ms) of the first-order kernel mfERG responses (N1, P1, and N2 waves) were obtained and grouped into five rings (Ring 1: Central 2°, Ring 2: 2-5°, Ring 3: 5-10°, Ring 4: 10-15°, Ring 5: >15°). The central macular thickness (CMT) was obtained using the macular thickness scan protocol of the OCT. Results: The mfERG data obtained were used to create a normative database. The amplitudes of the mfERG waves were maximum in the fovea and progressively decreased with increasing eccentricity (P = 0.0001). The latencies of the P1 and N2 waves were longest in the central ring and progressively shortened with eccentricity (P = 0.0001). No statistically significant correlations were observed between central ring 1 parameters and the CMT. Conclusion: This study establishes normative database for mfERG parameters in an emmetropic population. No statistically significant correlation was noted between CMT and mfERG parameters.
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