Effect of Taurine and Curcumin on In-Vitro Fertilization in NMRI Mice Treated with Acrylamide
| Autor: | Roza Saberi, Abbas Ahmadi, Zahra Khodabandeh, Sanaz Alaee |
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| Jazyk: | perština |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, Vol 30, Iss 5, Pp 4828-4841 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2228-5741 2228-5733 |
| Popis: | Introduction: The aim of this study was to evaluate the effect of taurine and curcumin on in vitro fertilization (IVF) in female mice treated with acrylamideand and its effect on malondialdehyde (MDA) concentration and total antioxidant capacity (TAC). Methods: A total of 48 adult female NMRI mice were randomly divided into 6 groups, including control, curcumin 200 mg / kg, taurine 150 mg / kg, acrylamide 5 mg / kg, acrylamide 5 mg / kg + curcumin 100 and 200, acrylamide 5 mg / kg + Taurine 75 and 150 mg / kg. The drugs were administered orally for 35 days, and then IVF rate, MDA and TAC concentrations were examined in each group. Results: The results showed a significant decrease in oocyte, fertilization percentage, 2, 4 and 8 cell, Compact and blastocytes embryos in the acrylamide group compared to the control (P |
| Databáze: | Directory of Open Access Journals |
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