EFFECT OF CEREBRAL VASOSPASM ON DISEASE OUTCOMES IN PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY
| Autor: | A. Y. Karpunin, S. S. Petrikov, L. T. Khamidova, V. V. Krylov |
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| Jazyk: | ruština |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Неотложная медицинская помощь, Vol 0, Iss 3, Pp 49-54 (2016) |
| Druh dokumentu: | article |
| ISSN: | 2223-9022 2541-8017 |
| Popis: | ABSTRACT. Cerebral vasospasm (CV) is an urgent issue in the treatment of patients with severe traumatic brain injury (STBI).OBJECTIVES. The aim of this study was to evaluate the effect of cerebral vasospasm on outcomes of STBI.MATERIAL AND METHODS. The study included 43 patients with isolated and assocoated STBI. The depression of consciousness in patients upon admission was 8 or less according to the Glasgow Coma Scale (GCS).RESULTS. Cerebral vasospasm was revealed in 33 (77%) patients. Groups were comparable according to age, type of TBI, GCS and average AP upon admission to hospital. The analysis of the disease outcomes according to GOS revealed significant between-group differences in the assessment of favorable outсomes (score 4–5, GOS), unfavorable outcomes (score 2–3, GOS) and deaths. In patients without CV and with moderate CV, the rate of cases with GOS 1 and GOS 2–3 was 30% (n=3) and 31% (n=5), respectively, and in patients with significant CV it was 82% (n=14).CONCLUSION. The development of significant cerebral vasospasm in patients with severe traumatic brain injury results in increased mortality by 21% and recovery with adverse neurological outcomes by 31%. The post-traumatic CV may cause secondary ischemic brain damage, resulting in considerable disturbance of cerebral oxygenation. |
| Databáze: | Directory of Open Access Journals |
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