Paradigm shift in radiation treatment planning over multiple treatment modalities

Autor:	Benjamin Insley, I-Chow Hsu, J Adam Martin Cunha
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	biological dose models inverse planning treatment planning Medical physics. Medical radiology. Nuclear medicine R895-920
Zdroj:	Journal of Medical Physics, Vol 46, Iss 3, Pp 135-139 (2021)
Druh dokumentu:	article
ISSN:	0971-6203 1998-3913
DOI:	10.4103/jmp.JMP_66_20
Popis:	The inverse planning simulated annealing optimization engine was used to develop a new method of incorporating biological parameters into radiation treatment planning. This method integrates optimization of a radiation schedule over multiple types of delivery methods into a single algorithm. We demonstrate a general procedure of incorporating a functional biological dose model into the calculation of physical dose prescriptions. This paradigm differs from current practice in that it combines biology-informed dose constraints with a physical dose optimizer allowing for the comparison of treatment plans across multiple different radiation types and fractionation schemes.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/e08a07b73efb4dbf9ea1ab6b89c6ae2f Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF