Epidemiology of infective endocarditis in French intensive care units over the 1997–2014 period—from CUB-Réa Network

Autor: Jérémie Joffre, Guillaume Dumas, Philippe Aegerter, Vincent Dubée, Naike Bigé, Gabriel Preda, Jean-Luc Baudel, Eric Maury, Bertrand Guidet, Hafid Ait-Oufella, on behalf of the CUB-Réa Network
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Critical Care, Vol 23, Iss 1, Pp 1-10 (2019)
Druh dokumentu: article
ISSN: 1364-8535
DOI: 10.1186/s13054-019-2387-8
Popis: Abstract Background Few studies focus only on severe forms of infective endocarditis, for which organ failure requires admission to an intensive care unit (ICU). This study aimed to describe demographical, comorbidities, organ failure, and pathogen-related characteristics in a population of critically ill patients admitted to ICU for infective endocarditis and to identify risk factors of in-ICU mortality. Methods Retrospective observational multicenter (N = 34) study of the CUB-Rea register, based on ICD-10 coding rules, between 1997 and 2014 in France including ICU patients managed for infective endocarditis. In-ICU mortality associated factors were assessed by multivariate logistic regression including an interrupted time analysis of three periods (1997–2003, 2004–2009, and 2010–2014). Results Four thousand four hundred five patients admitted in ICU for infective endocarditis were included. We observed an increase in endocarditis prevalence, as well as an increase in organ failure severity over the three periods. In addition, valve surgery was more frequently performed (27%, 31%, and 42%, P
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