Effect of Convallaria majalis on Kidney Function
| Autor: | Tooba Lateef, Hafsa Rukash, Faiza Bibi, Muhammad Bilal Azmi, Shamim Akhtar Qureshi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Journal of the Dow University of Health Sciences, Vol 4, Iss 3, Pp 94-97 (2010) |
| Druh dokumentu: | article |
| ISSN: | 1995-2198 2410-2180 |
| Popis: | Objective: To evaluate the effect o f Convallaria majalis on kidney function. The kidneys are vital organs thatperform a variety of important functions in our body. Primary and secondary causes o f kidney diseases producechanges in glomerular filtration rate that m ay leads to kidney failure. Blood parameters such as uric acid andcreatinine are used to assess kidney function. C. majalis (CM) commonly called as Lily o f the valley is aHomoeopathic remedy having valuable action on heart and also has diuretic action. Methods: In the present study, the effect o f CM was investigated on serum uric acid and creatinine, byadministrating orally 70% alcoholic extract o f CM (10 and 50 mg/kg), simvastatin (20 mg/kg), 0.05%dimethylsulphooxide (DMSO, 1ml/kg) and distilled w ater (1ml/kg) to test (A & B groups), positive, negativeand control rabbits respectively for 14 days consecutively once in a day. On completion o f trial, rabbits weresac rificed to co llec t b lo o d and serum was sep a rated to estimate uric acid and creatin in e levels. Results: Out of two tested doses, 10 mg/kg o f CM produced significant decrease in uric acid levels from 10.978.40mg/dL in test rabbits (Test A) when compared with control, negative & positive control groups (p |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|