| Autor: |
Tuba Bayindir, Yuksel Toplu, Baris Otlu, Yusuf Yakupogullari, Ozge Yildirim, Mahmut Tayyar Kalcioglu |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Brazilian Journal of Otorhinolaryngology, Vol 81, Iss 3, Pp 307-311 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
1808-8686 |
| DOI: |
10.1016/j.bjorl.2014.08.018 |
| Popis: |
INTRODUCTION: There is an ongoing debate about the existence and effects of Helicobacter pylori (Hp) in adenotonsillar tissue. OBJECTIVE: A clinical study was conducted to assess the existence of Hp in the adenoid and/or adenotonsillar tissues, which were surgically excised due to chronic adenotonsillitis. METHODS: Phosphoglucosamine mutase gene for the detection of Hp and cytotoxin-associated gene as virulence gene were examined in 84 adenotonsillar tissues obtained from 64 patients and patients' serum by using polymerase chain reaction. RESULTS: Hp IgG was detected in 57 (89%) patients' serum. A total of seven tissue samples from 64 patients (10.9%) were found positive for Hp DNA, of which five were adenoids and two were tonsil tissues. All polymerase chain reaction positive samples were also positive for the cytotoxin-associated gene, which is a virulence determinant for the organism. CONCLUSION: This study suggests that children are exposed to Hp at an early age of their life in this province. Hp may have a role in the pathogenesis of chronic adenotonsillitis, especially in endemic areas. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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