| Autor: |
Nicolas-Frédéric Lipp, Romain Gautier, Maud Magdeleine, Maxime Renard, Véronique Albanèse, Alenka Čopič, Guillaume Drin |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-019-11780-y |
| Popis: |
Osh6p and Osh7p are yeast lipid transfer proteins (LTPs) that must transiently interact with membranes but how they escape from the electrostatic attraction of the plasma membrane is unclear. Here authors show that Osh6p reduces its avidity for anionic membranes once it captures PS or PI4P, due to a molecular lid closing its lipid-binding pocket. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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