| Autor: |
Yitong Lv, Lei Huang, Junhu Wang, Hui He, Libo Song, Jia He, Lida Xu, Changyuan Yu, Ying Mei, Qi Gao |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Frontiers in Immunology, Vol 14 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1664-3224 |
| DOI: |
10.3389/fimmu.2023.1282612 |
| Popis: |
BackgroundThe immune background of the overall population before and after the outbreak of SARS-CoV-2 in China remains unexplored. And the level of neutralizing antibodies is a reliable indicator of individual immunity.ObjectivesThis study aimed to assess the immune levels of different population groups during a viral outbreak and identify the factors influencing these levels.MethodsWe measured the levels of neutralizing antibodies in 12,137 participants using the COVID19 Neutralizing Antibody Detection kit. The dynamics of neutralizing antibodies were analyzed using a generalized additive model, while a generalized linear model and multi-factor analysis of variance were employed to investigate the influencing factors. Additionally, statistical methods were used to compare neutralizing antibody levels among subgroups of the real-world population.ResultsParticipants who received booster doses exhibited significantly higher levels of neutralizing antibodies compared to those who received only one or two doses (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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