Citrate-based fluorometric sensor for multi-halide sensing

Autor: Dingbowen Wang, Tunan Xia, Yuqi Wang, Yizhu Chen, Chenji Zhang, William Murray, Adam Thomas Schultz, Zhiwen Liu, Jian Yang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Smart Materials in Medicine, Vol 3, Iss , Pp 374-381 (2022)
Druh dokumentu: article
ISSN: 2590-1834
DOI: 10.1016/j.smaim.2022.05.001
Popis: Halides play important roles in human health and environmental monitoring. However, different halides interfere with each other in current measurement methods. Simultaneous sensing of multiple halides in a fast and low-cost manner remains a challenge. Here, we report a fluorometric multi-halide sensing method by using a single citrate-based fluorophore, CA-Cys, on a custom-made portable device. The fluorescence emitted by CA-Cys is quenched due to the dynamic quenching of halide ions; the sensitivities vary from halide types and pH, providing the capability to obtain multiple Stern-Volmer equations at various pH values. The concentration of each halide can then be obtained by solving the resultant set of equations. A mM scale detection limit is demonstrated, which is suitable for halide wastewater monitoring. A proof-of-concept smartphone-based portable device is also fabricated and tested. The results from the fluorometer and portable device indicated that our multi-halide system is promising for real-world multi-halide sensing applications. This work represents a new direction in developing portable, low-cost, and simultaneous multi-halide sensing technologies.
Databáze: Directory of Open Access Journals