Expression profile of LncRNA ANRIL, miR-186, miR-181a, and MTMR-3 in patients with preeclampsia

Autor: Shymaa E. Ayoub, Olfat G. Shaker, Rehab Abdelhamid Aboshama, Mohamed K. Etman, Abeer A. Khalefa, Mohamed M. khamiss Abd elguaad, Othman M. Zaki, Doaa Y. Ali, Nada F. Hemeda, Amal Amin, Marwa A. Ali
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Non-coding RNA Research, Vol 8, Iss 4, Pp 481-486 (2023)
Druh dokumentu: article
ISSN: 2468-0540
DOI: 10.1016/j.ncrna.2023.06.001
Popis: Preeclampsia (PE) is a leading cause of maternal and neonatal morbidity and mortality worldwide. Several studies demonstrated the role of lncRNAs and miRNAs in the pathogenesis of preeclampsia; the aim was to detect the expression profiles of serum LncRNA ANRIL, miR-186, miR-181a, and MTMR-3 in patients with preeclampsia. The study included 160 subjects divided into 80 subjects considered as a control group, 80 patients with preeclampsia. We found that there was a significant difference between the preeclampsia and control groups with up-regulation of miR-186 median (IQR) = 4, 29 (1.35–7.73) (P
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