Histopathology of Endometrial Stromal Sarcoma with Emphasis on Immunohistochemistry Marker Expression: Report of Three Cases
| Autor: | Narayanamoorthy Keerthyraj, Vigneswaramoorthi Vinayagamoorthi, Erli Amel Ivan, V Sriram, Govindasamy Revathi, Ramya Gandhi |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Medical Journal of Dr. D.Y. Patil Vidyapeeth, Vol 17, Iss Suppl 1, Pp S219-S223 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2589-8302 2589-8310 |
| DOI: | 10.4103/mjdrdypu.mjdrdypu_51_23 |
| Popis: | Endometrial stromal tumors are rare uterine mesenchymal neoplasms. Endometrial stromal sarcomas (ESSs) are of endometrial stromal origin that accounts for approximately 1% of all uterine malignant neoplasms. ESS is classified into endometrial stromal nodule (ESN), low-grade ESS (LG-ESS), high-grade endometrial stromal sarcoma (HG-ESS), and undifferentiated uterine sarcoma (UUS). The usual clinical presentation of ESS is abnormal uterine bleeding in about 90% of women and uterine enlargement in about 70%, followed by dysmenorrhea and pain in the abdomen in some patients. Clinically, leiomyoma, endometrial polyp, and other malignant entities enter the differential diagnosis. Gross presentation and microscopic examination, along with immunohistochemistry marker expression and clinical correlation, are mandatory to understand their biological nature, prognosis, and treatment outcome. |
| Databáze: | Directory of Open Access Journals |
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