Efficacy of Botulinum Toxin Injections in the Treatment of Various Types of Facial Region Disorders

Autor: Arzu Çoban, Zeliha Matur, Haşmet A. Hanağası, Yeşim Parman
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Türk Nöroloji Dergisi, Vol 18, Iss 4, Pp 155-161 (2012)
Druh dokumentu: article
ISSN: 1301-062X
1309-2545
DOI: 10.4274/Tnd.26097
Popis: OBJECTIVE: Local injection of botulinum toxin is a highly effective treatment option for a wide range of movement disorders and there are reliable sources of information on its indications, effects and safety in clinical practice. In this study, we report our experience with botulinum toxin in the treatment of facial region disorders. METHODS: Patients who had been followed in the Botulinum Toxin Outpatient Clinic of the Neurology Department were retrospectively evaluated. Two preparations of botulinum toxin type A (BT-A) were used. The efficacy of BT-A injections was rated according to the improvement in symptoms as follows: marked - 75-100% improvement, good - 50-74%, moderate - 25-49%, and insufficient - less than 25% symptom relief. RESULTS: One hundred eighty-two patients (73 male, 109 female) with various facial region disorders were included. The efficacy rates for patients who had very good and good improvement were high in the treatment of blepharospasm, hemifacial spasm, facial synkinesis, and Meige syndrome and moderate for oromandibular dystonia and hypersalivation. Ptosis was the most common side effect. CONCLUSION: According to our results, botulinum toxin was very effective treatment for blepharospasm, Meige syndrome, hemifacial spasm and facial synkinesis, whereas it demonstrated good efficacy in oromandibular dystonia and hypersalivation
Databáze: Directory of Open Access Journals