| Autor: |
Zhuanbo Yang, Xiaowen Lan, Zhou Huang, Yong Yang, Yu Tang, Hao Jing, Jianyang Wang, Jianghu Zhang, Xiang Wang, Jidong Gao, Jing Wang, Lixue Xuan, Yi Fang, Jianming Ying, Yexiong Li, Xiaobo Huang, Shulian Wang |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Breast, Vol 53, Iss , Pp 143-151 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1532-3080 |
| DOI: |
10.1016/j.breast.2020.08.001 |
| Popis: |
Objective: To develop a nomogram for predicting the possibility of four or more positive nodes in breast cancer patients with 1–3 positive sentinel lymph nodes (SLN). Materials and methods: Retrospective analysis of data of patients from two institutions was conducted. The inclusion criteria were: invasive breast cancer; clinically node negative; received lumpectomy or mastectomy plus SLN biopsy followed by axillary lymph node dissection (ALND); and pathologically confirmed T1-2 tumor, with 1–3 positive SLNs. Patients from one institution formed the training group and patients from the other the validation group. Univariate and multivariate analyses were performed to identify the predictors of four or more positive nodes. These predictors were used to build the nomogram. The area under the receiver operating characteristic curve (AUC) was calculated to assess the accuracy of the model. Results: Of the 1480 patients (966 patients in the training group, 514 in the validation group), 306 (20.7%) had four or more positive nodes. Multivariate stepwise logistic regression showed number of positive (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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