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Daniel López-López,1 María Martínez-Vázquez,1 Marta Elena Losa-Iglesias,2 César Calvo-Lobo,3 David Rodríguez-Sanz,4 Patricia Palomo-López,5 Ricardo Becerro-de-Bengoa-Vallejo6 1Research, Health and Podiatry Unit, Department of Health Sciences, Faculty of Nursing and Podiatry, Universidade da Coruña, Ferrol, Spain; 2Faculty of Health Sciences, Universidad Rey Juan Carlos, Madrid, Spain; 3Nursing and Physical Therapy Department, Institute of Biomedicine (IBIOMED), Universidad de León, Ponferrada, León, Spain; 4School of Sports Science, European University, Villaviciosa de Odón, Madrid, Spain; 5University Center of Plasencia, Universidad de Extremadura, Extremadura, Spain; 6School of Nursing, Physiotherapy and Podiatry, Universidad Complutense de Madrid, Madrid, Spain Purpose: The aim of this study was to compare the health-related quality of life impact related to foot health and health in general in older adults with lesser toe deformities (LTD) and without any foot conditions. Methods: A case–control observational study was carried out following the Strengthening the Reporting of Observational Studies in Epidemiology criteria. A total of 100 older adults with a mean age of 74.39±6.02 years were recruited at an outpatient clinic; 50 of these subjects had LTD (case group) and 50 subjects were without any foot conditions (control group). Presence of LTD was determined in both feet using the Kelikian push-up test, and the Foot Health Status Questionnaire scores were self-reported.Results: The case group showed lower scores in quality of life in relation to health in general and to foot health specifically. Statistically significant differences (p |