Positive effect of if-channel’s blocker ivabradine therapy in a patient with ischemic chronic heart failure with preserved left ventricle ejection fraction and hereditary thrombophilia (clinical case)
| Autor: | Iurii N. Belenkov, Elena V. Privalova, Irina S. Ilgisonis, Iuliia I. Naymann, Alexey V. Zhito |
|---|---|
| Jazyk: | English<br />Russian |
| Rok vydání: | 2019 |
| Předmět: |
хроническая сердечная недостаточность
хроническая сердечная недостаточность с сохранной фракцией выброса ишемическая болезнь сердца ивабрадин частота сердечных сокращений тахикардия Diseases of the circulatory (Cardiovascular) system RC666-701 Diseases of the endocrine glands. Clinical endocrinology RC648-665 |
| Zdroj: | КардиоСоматика, Vol 10, Iss 3, Pp 79-84 (2019) |
| Druh dokumentu: | article |
| ISSN: | 2221-7185 2658-5707 22217185 |
| DOI: | 10.26442/22217185.2019.3.190544 |
| Popis: | Chronic heart failure is one of the leading causes of mortality among patients with cardiovascular diseases. Current therapeutic methods for treating patients with chronic heart failure do not always provide a significant improvement in main intermediate and final outcomes. According to the neurohumoral theory of chronic heart failure development, an antagonism of the sympathoadrenal system with b-blockers is pathogenetically substantiated, and the drugs of this group are one of the first-line treatment for chronic heart failure. The selection of heart rate-reducing therapy in patients with chronic heart failure caused by ischemia, can often be difficult due to development of b-blockers side effects, b-blockers intolerance and/or due to the presence of contraindications at severe comorbid pathology. This article presents a clinical case of an effective administration of ivabradine, a drug of if-channel inhibitors group, in combination with b-blockers to a patient with chronic heart failure with a preserved ejection fraction. |
| Databáze: | Directory of Open Access Journals |
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