| Autor: |
Stella Stabouli, Vasilios Kotsis, Olga Maliachova, Nikoleta Printza, Athanasia Chainoglou, Athanasios Christoforidis, Anna Taparkou, John Dotis, Evangelia Farmaki, Dimitrios Zafeiriou |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
International Journal of Cardiology. Hypertension, Vol 4, Iss , Pp 100025- (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2590-0862 |
| DOI: |
10.1016/j.ijchy.2020.100025 |
| Popis: |
Background and aims: Matrix metalloproteinases (MMPs) may contribute to the pathogenesis of arterial stiffness inducing extracellular matrix remodeling. We aimed to compare MMP-2 and -9 levels in children with chronic kidney disease (CKD), type 1 diabetes (without chronic kidney disease) and healthy control and to investigate associations of MMPs levels with cardiovascular risk factors and markers of arterial stiffness. Methods: The study population included 33 CKD, 18 type 1 diabetes patients, and 24 healthy controls. MMP-2, MMP-9, office blood pressure, pulse wave analysis, and carotid-femoral pulse wave velocity (cfPWV) measurements were performed. Results: MMP-2 levels were higher in the CKD compared to the diabetes and control groups (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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