Long COVID 19 Syndrome: Is It Related to Microcirculation and Endothelial Dysfunction? Insights From TUN-EndCOV Study

Autor: Salma Charfeddine, Hassen Ibn Hadj Amor, Jihen Jdidi, Slim Torjmen, Salma Kraiem, Rania Hammami, Amine Bahloul, Nesrine Kallel, Nedia Moussa, Imen Touil, Aiman Ghrab, Jamel Elghoul, Zineb Meddeb, Yamina Thabet, Samir Kammoun, Kamel Bouslama, Sami Milouchi, Salem Abdessalem, Leila Abid
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Druh dokumentu: article
ISSN: 2297-055X
DOI: 10.3389/fcvm.2021.745758
Popis: The COVID-19 disease is a multisystem disease due in part to the vascular endothelium injury. Lasting effects and long-term sequelae could persist after the infection and may be due to persistent endothelial dysfunction. Our study focused on the evaluation of endothelial quality index (EQI) by finger thermal monitoring with E4 diagnosis Polymath in a large cohort of long COVID-19 patients to determine whether long-covid 19 symptoms are associated with endothelial dysfunction. This is a cross-sectional multicenter observational study with prospective recruitment of patients. A total of 798 patients were included in this study. A total of 618 patients (77.4%) had long COVID-19 symptoms. The mean EQI was 2.02 ± 0.99 IC95% [1.95–2.08]. A total of 397 (49.7%) patients had impaired EQI. Fatigue, chest pain, and neuro-cognitive difficulties were significantly associated with endothelium dysfunction with an EQI
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