Infectious endocarditis caused by Bartonella henselae associated with infected pets: two case reports

Autor: Jonathan Gonçalves-Oliveira, Paulo Vieira Damasco, Matheus Ribeiro da S. Assis, Dominique E. Freitas, Adonai Alvino Pessoa Junior, Luiza S. de Sousa, Nicollas G. Rodrigues, Paula H. Damasco, Pedro F. Ribeiro, Giovanna F. Barbosa, Namir S. Moreira, Jeferson F. Guedes, Henrique M. da Rocha Coutinho, Kalil Madi, Elba R. Sampaio de Lemos
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-7 (2023)
Druh dokumentu: article
ISSN: 1752-1947
DOI: 10.1186/s13256-023-03839-8
Popis: Abstract Background Blood culture-negative infective endocarditis is a potentially severe disease that can be associated with infectious agents such as Bartonella spp., Coxiella burnetti, Tropheryma whipplei, and some fungi. Case presentation Reported here are two cases of blood culture-negative infective endocarditis in patients with severe aortic and mitral regurgitation in Brazil; the first case is a 47-year-old white man and the second is a 62-year-old white woman. Bartonella henselae deoxyribonucleic acid was detectable in the blood samples and cardiac valve with vegetation paraffin-fixed tissue samples. Additionally, an investigation was carried out on patients’ pets, within the context of One Health, and serum samples collected from cats and dogs were reactive by indirect immunofluorescence assay. Conclusions Even though the frequency of bartonellosis in Brazil is unknown, physicians should be aware of the possibility of blood culture-negative infective endocarditis caused by Bartonella, particularly in patients with weight loss, kidney changes, and epidemiological history for domestic animals.
Databáze: Directory of Open Access Journals
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