Relationship Between CRP, Procalcitonin, I/T Ratio and The Incidence of Sepsis in Children

Autor: Nissa Salsabila WINARNO, Nahwa ARKHAESI, MULYONO, Galuh HARDANINGSIH, Edward Kurnia Setiawan LIMIJADI
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Modern Medicine, Vol 30, Iss 3, Pp 227-233 (2023)
Druh dokumentu: article
ISSN: 1223-0472
2360-2473
DOI: 10.31689/rmm.2023.30.3.227
Popis: Background: Sepsis is body immune response due to infection. Sepsis is a medical emergency condition with high-risk of mortality. WHO in 2018 stated that every year there were 2.9 million cases of death due to sepsis. Several markers can be used to support evidence of sepsis in children, such as C-Reactive Protein (CRP), Procalcitonin, and IT ratio. This study will assess 3 markers namely C-Reactive Protein, procalcitonin, and IT ratio that have not found in previous studies. Aim: To analyse association between inflammatory parameters and the incidence of sepsis in children. Methods: This study is an observational analytic study with a cross-sectional approach that analyses the medical records of paediatric patients in the PICU of RSUP Dr. Kariadi, Semarang from January 2019 – August 2022. The data used are secondary data taken from medical records and then analysed descriptively for patient characteristics. The variables of this study were then analysed bivariate using the chi-square or fisher test then analysed multivariate by logistic regression analysis. Result: Correlation between C-Reactive Protein levels, Procalcitonin, and IT ratio with the incidence of sepsis in children p
Databáze: Directory of Open Access Journals