Performance levels of four Latin American laboratories for the serodiagnosis of Chagas disease in Mexican sera samples

Autor: Alejandro O Luquetti, Bertha Espinoza, Ignacio Martínez, Nidia Hernández-Becerril, Carlos Ponce, Elisa Ponce, Pedro A Reyes, Oscar Hernández, Ruth López, Victor Monteón
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Memorias do Instituto Oswaldo Cruz, Vol 104, Iss 5, Pp 797-800 (2009)
Druh dokumentu: article
ISSN: 0074-0276
1678-8060
DOI: 10.1590/S0074-02762009000500023
Popis: In nearly all of the previous multicentre studies evaluating serological tests for Trypanosoma cruzi infection, sera samples from Central or South American countries have been used preferentially. In this work we compared the reliability of the serological tests using Mexican sera samples that were evaluated in four independent laboratories. This included a reference laboratory in Brazil and three participant laboratories, including one in Central America and two in Mexico. The kappa index between Brazilian and Honduran laboratories reached 1.0 and the index for the Mexican laboratories reached 0.94. Another finding of this study was that the source of antigen did not affect the performance of the serological tests.
Databáze: Directory of Open Access Journals