| Autor: |
Dominika J. Walaszek, Magdalena Jawiczuk, Jakub Durka, Olga Drapała, Dorota Gryko |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 2076-2084 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1860-5397 |
| DOI: |
10.3762/bjoc.15.205 |
| Popis: |
Organocatalytic α-oxygenation of chiral aldehydes with photochemically generated singlet oxygen allows synthesizing chiral 3-substituted 1,2-diols. Stereochemical results indicate that the reaction in the presence of diarylprolinol silyl ethers is highly diastereoselective and that the configuration of a newly created stereocenter at the α-position depends predominantly on the catalyst structure. The absolute configuration of chiral 1,2-diols has been unambiguously established based on electronic circular dichroism (ECD) and TD-DFT methods. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
