Acute Colchicine Poisoning Treated with Granulocyte Colony Stimulating Factor and Transfusion

Autor:	Sung-Hwa Lee, Sung-Wook Park, Sang-Kyoon Han, Soon-Chang Park
Jazyk:	English<br />Korean
Rok vydání:	2015
Předmět:	colchicine neutropenia toxicity Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Zdroj:	Korean Journal of Critical Care Medicine, Vol 30, Iss 3, Pp 207-211 (2015)
Druh dokumentu:	article
ISSN:	2383-4870 2383-4889
DOI:	10.4266/kjccm.2015.30.3.207
Popis:	Colchicine poisoning is rare but can cause potentially life-threatening toxic complications such as hypovolemic shock, cardiovascular collapse and multiple organ failure. In this case report, we describe a case of a 20-year-old female who presented to the emergency department after suicidal ingestion of a toxic dose of colchicine. She developed thrombocytopenia, neutropenia and acute respiratory distress syndrome that required blood transfusion and administration of granulocyte colony stimulating factor for the prevention of infectious complications. With regard to the clinical manifestations of colchicine toxicity, we discussed suggested mechanisms.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/ee081439a9714b1595fa653e1abb3de7 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF