| Autor: |
Thito Y. Bezerra da Paz, Leonardo H. Almeida Hernández, Sandro Patroca da Silva, Fábio Silva da Silva, Bruno C. Veloso de Barros, Livia M. Neves Casseb, Ricardo J. de Paula Souza e Guimarães, Pedro F. da Costa Vasconcelos, Ana C. Ribeiro Cruz |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Viruses, Vol 15, Iss 5, p 1150 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1999-4915 |
| DOI: |
10.3390/v15051150 |
| Popis: |
As part of a continuous effort to investigate the viral communities associated with wild mammals at the human–animal interface in an Amazonian metropolitan region, this study describes the detection of a novel rodent-borne arterivirus. A sample containing pooled organs of Oecomys paricola was submitted to RNA sequencing, and four sequences taxonomically assigned as related to the Arteriviridae family were recovered, corresponding to an almost complete genome of nearly 13 kb summed. In the phylogenetic analysis with the standard domains used for taxa demarcation in the family, the tentatively named Oecomys arterivirus 1 (OAV-1) was placed within the clade of rodent- and porcine-associated viruses, corresponding to the Variarterivirinae subfamily. The divergence analysis, based on the same amino acid alignment, corroborated the hypothesis that the virus may represent a new genus within the subfamily. These findings contribute to the expansion of the current knowledge about the diversity, host and geographical range of the viral family. Arterivirids are non-human pathogens and are usually species-specific, but the susceptibility of cell lines derived from different organisms should be conducted to confirm these statements for this proposed new genus in an initial attempt to assess its spillover potential. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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