Brain tissue microstructural and free-water composition 13 years after very preterm birth

Autor: Claire Kelly, Thijs Dhollander, Ian H Harding, Wasim Khan, Richard Beare, Jeanie LY Cheong, Lex W Doyle, Marc Seal, Deanne K Thompson, Terrie E Inder, Peter J Anderson
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: NeuroImage, Vol 254, Iss , Pp 119168- (2022)
Druh dokumentu: article
ISSN: 1095-9572
08040109
DOI: 10.1016/j.neuroimage.2022.119168
Popis: There have been many studies demonstrating children born very preterm exhibit brain white matter microstructural alterations, which have been related to neurodevelopmental difficulties. These prior studies have often been based on diffusion MRI modelling and analysis techniques, which commonly focussed on white matter microstructural properties in children born very preterm. However, there have been relatively fewer studies investigating the free-water content of the white matter, and also the microstructure and free-water content of the cortical grey matter, in children born very preterm. These biophysical properties of the brain change rapidly during fetal and neonatal brain development, and therefore such properties are likely also adversely affected by very preterm birth. In this study, we investigated the relationship of very preterm birth (
Databáze: Directory of Open Access Journals
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