| Autor: |
Girma Tekle Gebremariam, Gebremedhin Beedemariam Gebretekle, Wondemagegnhu Tigneh, Biruck Gashawbeza, Alemu Belayneh, Abdu Mengesha, Abraham G. Welie, Eskinder Eshetu Ali |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Health and Quality of Life Outcomes, Vol 22, Iss 1, Pp 1-11 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1477-7525 |
| DOI: |
10.1186/s12955-024-02305-3 |
| Popis: |
Abstract Background Despite being a widely used generic measure of health-related quality of life worldwide, there is limited evidence on the psychometric properties of the EuroQoL Five-dimensions five level (EQ-5D) among cervical cancer patients in Ethiopia. Objective To evaluate psychometric properties of the Amharic version of EQ-5D among Ethiopian cervical cancer patients. Methods A longitudinal survey of cervical cancer patients receiving treatment at two Ethiopian tertiary care facilities was conducted from March 2022 to July 2023. Participants completed the EQ-5D and the European Organization for Research and Therapy of Cancer (EORTC QLQ-C30) at baseline and after three months on treatment. Effect size and standardized response mean were used to assess responsiveness. Anchor-based and distribution-based methods were used to calculate the minimal clinically important difference (MCID). Minimal detectable change (MDC) ratios were computed at the individual and group levels. Statistical significance was determined at p 0.6) and the instrument showed good discriminate validity between patients with different health states. The effect size ranged between − 0.12 and 0.60 for the EQ-5D index value and − 0.12 to 1.16 for the EQ VAS, indicating small to large responsiveness. The average (range) MCID value of the EQ-5D index was 0.10–0.15. The findings showed that MCID to MDC ratios at the group level were more clinically meaningful than the individual level. Conclusion The EQ-5D effectively detected changes and discriminate patients with different levels of health. While group-level MCIDs were established in this study, further studies are recommended to prove its usefulness at the individual-level. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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