Follow-up of neurocysticercosis patients after treatment using an antigen detection ELISA
| Autor: | Nguekam, Zoli A.P., Ongolo-Zogo P., Dorny P., Brandt J., Geerts S. |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2003 |
| Předmět: | |
| Zdroj: | Parasite, Vol 10, Iss 1, Pp 65-68 (2003) |
| Druh dokumentu: | article |
| ISSN: | 1252-607X 1776-1042 |
| DOI: | 10.1051/parasite/2003101p65 |
| Popis: | Seven patients with active neurocysticercosis (NCC) received an eight days treatment with albendazole and were followed up using computed tomography (CT-scan) and a monoclonal antibody based ELISA for the detection of circulating antigen (Ag-ELISA). Only three patients were cured as was shown by CT-scan and by the disappearance of circulating antigens one month after treatment. After a second course of albendazole therapy, two other patients became seronegative. CT-scan showed the disappearance of viable cysts in all persons who became seronegative whereas patients who were not cured remained seropositive. These preliminary results show that this Ag-ELISA is a promising technique for monitoring the success of treatment of NCC patients because of the excellent correlation between the presence of circulating antigens and of viable brain cysts. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|