Direct pulmonary infiltrates as an initial manifestation of chronic lymphocytic leukemia

Autor: Atsuki Fukada, Hideki Yasui, Tomoaki Uto, Shioto Suzuki, Jun Sato, Shiro Imokawa, Takafumi Suda
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Respiratory Medicine Case Reports, Vol 25, Iss , Pp 282-285 (2018)
Druh dokumentu: article
ISSN: 2213-0071
DOI: 10.1016/j.rmcr.2018.10.011
Popis: An 85-year-old man who did not have any hematological or respiratory disorders was transferred to our hospital because of progressive dyspnea. Computed tomography (CT) findings showed ground-glass opacities with a centrilobular distribution and centrilobular micronodules with a “tree-in-bud” pattern. A biopsy of the lungs showed lymphocytic infiltrations in the parenchyma and these were positive for B cell markers. A diagnosis of chronic lymphocytic leukemia (CLL) was made and direct pulmonary involvement of CLL was confirmed simultaneously. One month after initiation of chemotherapy, his symptoms improved and a chest CT scan showed marked resolution. Pulmonary infiltrates of CLL should be included in the differential diagnosis when these signs are encountered on CT. Keywords: Chronic lymphocytic leukemia, Pulmonary infiltrate, Centrilobular micronodule, “Tree-in-bud” pattern
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