| Autor: |
Kamilu M. Karaye, Naser A. Ishaq, Hadiza Sai'du, Sulaiman A. Balarabe, Bashir G. Ahmed, Umar G. Adamu, Idris Y. Mohammed, Isa Oboirien, Ejiroghene M. Umuerri, Abaram C. Mankwe, Vincent Y. Shidali, Sotonye Dodiyi‐Manuel, Paschal Njoku, Taiwo Olunuga, Veronica Josephs, Amam C. Mbakwem, Okechukwu S. Ogah, Jamilu Tukur, Basil Okeahialam, Simon Stewart, Michael Henein, Karen Sliwa, Peripartum Cardiomyopathy in Nigeria (PEACE) Registry Investigators |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
ESC Heart Failure, Vol 8, Iss 4, Pp 3257-3267 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2055-5822 |
| DOI: |
10.1002/ehf2.13463 |
| Popis: |
Abstract Aims The prospective, multicentre Peripartum Cardiomyopathy in Nigeria (PEACE) registry originally demonstrated a high prevalence of peripartum cardiomyopathy (PPCM) among patients originating from Kano, North‐West Nigeria. In a post hoc analysis, we sought to determine if this phenomenon was characterized by a differential case profile and outcome among PPCM cases originating elsewhere. Methods and results Overall, 199 (81.6%) of a total 244 PPCM patients were recruited from three sites in Kano, compared with 45 patients (18.4%) from 11 widely dispersed centres across Nigeria. Presence and extent of ventricular myocardial remodelling during follow‐up, relative to baseline status, were assessed by echocardiography. During median 17 months follow‐up, Kano patients demonstrated significantly better myocardial reverse remodelling than patients from other sites. Overall, 50.6% of patients from Kano versus 28.6% from other regions were asymptomatic (P = 0.029) at study completion, with an accompanying difference in all‐cause mortality (17.6% vs. 22.2% respectively, P = 0.523) not reaching statistical significance. Alternatively, 135/191 (84.9%) of Kano patients had selenium deficiency ( |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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